Common Use

Symmetrel, known by its generic name amantadine, is a medication used for treating and managing certain viral infections and symptoms of Parkinson’s disease. It is effective in treating influenza A by preventing the virus from multiplying, and it can also be used for prevention during flu outbreaks. In addition to its antiviral properties, Symmetrel helps manage symptoms of Parkinson's disease and other movement disorders, such as stiffness, shaking, and difficulty moving. By affecting dopamine levels in the brain, it helps improve muscle control and reduces symptoms like rigidity and tremors.

Dosage and Direction

Symmetrel is available in capsule, tablet, and syrup forms, allowing for flexible dosing options. The dosage depends on the condition being treated, the patient’s age, and how they respond to the medication. For Parkinson’s disease, the typical starting dose for adults is 100 mg taken once or twice daily. For treating influenza, the dosage is usually 200 mg per day, either as a single dose or divided into two doses. For children, the dosage will be based on weight and age.

Symmetrel should be taken with or without food as instructed by your doctor. To reduce the risk of side effects, take it at the same time each day, and avoid adjusting the dose without consulting your healthcare provider. If you are taking the syrup, use a proper measuring device to ensure accurate dosing.

Precautions

Before using Symmetrel, inform your doctor if you have any medical conditions, particularly kidney disease, liver issues, heart conditions, or a history of mental health disorders such as depression or psychosis. Since Symmetrel can sometimes cause drowsiness or dizziness, avoid driving or operating heavy machinery until you know how the medication affects you. Older adults may be more sensitive to the side effects, especially dizziness and lightheadedness, increasing the risk of falls.

If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits with your doctor. While Symmetrel may be used during pregnancy if necessary, it is important to evaluate its safety with your healthcare provider. Additionally, avoid consuming alcohol while on Symmetrel, as it can increase side effects like dizziness and confusion.

Contraindications

Symmetrel is contraindicated in individuals with a known allergy to amantadine or any of the ingredients in the medication. Patients with untreated angle-closure glaucoma should avoid this medication, as it may increase eye pressure. Symmetrel is also not recommended for people with severe kidney disease, as it is processed by the kidneys and could lead to toxic levels in the body. Additionally, individuals with severe psychotic disorders or uncontrolled mental health conditions should not use Symmetrel unless specifically advised by a doctor.

Possible Side Effects

Common side effects of Symmetrel include dizziness, lightheadedness, nausea, and blurred vision. Some individuals may also experience dry mouth, constipation, or trouble sleeping. These effects are usually mild and tend to subside as your body adjusts to the medication. However, if these symptoms persist or worsen, contact your healthcare provider.

In rare cases, Symmetrel can cause more serious side effects, such as mood changes, hallucinations, and swelling of the hands or feet. A rare but serious side effect, known as neuroleptic malignant syndrome, can cause muscle stiffness, high fever, and irregular heart rate. Seek immediate medical attention if you experience these symptoms. Allergic reactions, while uncommon, may include rash, itching, swelling, severe dizziness, and trouble breathing, and require urgent medical care.

Drug Interaction

Symmetrel can interact with various other medications, so it is important to inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements. Avoid combining Symmetrel with other medications that affect dopamine, such as certain antipsychotic drugs, as this can increase the risk of side effects. Other drugs, like diuretics (water pills), may increase the risk of side effects by affecting the amount of amantadine in your body. Combining Symmetrel with alcohol can intensify dizziness and drowsiness, so it’s best to avoid alcohol while taking this medication.

If you are taking medications for mental health conditions, seizures, or high blood pressure, your doctor may need to adjust your dose or monitor you more closely to avoid potential interactions.

Missed Dose

If you miss a dose of Symmetrel, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

Overdose

In case of an overdose, seek immediate medical attention. Symptoms of a Symmetrel overdose may include severe dizziness, fainting, irregular heartbeat, confusion, or hallucinations. Overdosing on Symmetrel can lead to serious complications, particularly affecting the heart and nervous system, so prompt treatment is essential.

Storage

Store Symmetrel at room temperature, between 20°C to 25°C (68°F to 77°F), away from light and moisture. Keep the medication in its original container, tightly closed, and out of reach of children and pets. Avoid storing it in humid areas like bathrooms, as moisture can reduce its effectiveness. If the medication has expired or is no longer needed, dispose of it properly according to local disposal regulations. Do not flush it down the toilet unless advised by your healthcare provider.

In summary, Symmetrel is a versatile medication that helps manage both viral infections and symptoms of Parkinson’s disease. By following the prescribed dosage, observing necessary precautions, and being aware of potential interactions and side effects, you can use Symmetrel safely to improve your quality of life. Always consult your healthcare provider for guidance on dosage adjustments and report any concerning symptoms for further evaluation.

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